Perioperative antibiotic prophylaxis in spinal surgery

Study design : Complete audit cycle. Introduction To highlight the unjustified overuse of perioperative antibiotics in clean non-instrumented lumbar spinal surgeries. convince orthopedic surgeons a methodological way local field comparison between common practice on use prophylaxis (PAP) surgeries and ideal according to “The guidelines published by North American Spine Society (NASS)”. Methods A complete cycle had been done. One hundred eight patients underwent tertiary spine center, during period from 1st April 31st June 2017 (primary period) 8th May 21st November 2018 (re-audit period). Group I: group ( n = 54) was given usual regimen (IV first-generation cephalosporin for 1–6 days, followed oral antibiotics, till removal stitches) II: re-audit received only IV one day). The study protocol approved our institution’s Ethical Committee (17100582). Results This showed wide gap international standards prescribing practices calls multiple interventions improve practice. Out 108 patients, case (1.85%) developed surgical site infection (SSI) (Group I). difference rates two groups statistically insignificant. Conclusion single-day postoperative dose effectively prevents wound following surgery is not associated with higher rate.